Colorectal cancer is a leading cause of cancer death in the US. Yet, despite knowing they face a raised risk, some patients aren’t following the doctor's orders for routine screenings. I'm Miranda Savioli with your latest health news.
A recent study looked at whether telling patients how at risk they were for colorectal cancer based on genetic tests would motivate them to have routine screenings. Researchers found that patients who knew they had a high risk were not more likely to have routine screenings than patients who had an average risk or did not know their risk. They also found patients with a college degree were more likely than those without one to have routine screenings.
Since these screenings can identify cancer early and raise chances of survival, ask your doctor which tests are right for you.
Taken from DailyRx.
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Pembrolizumab has been developed and approved to do be sold under the name Keytruda® in the US, a humanized monoclonal antibody against the programmed death receptor-1 (PD-1) protein, has been developed by Merck & Co for the treatment of cancer. This article summarizes the milestones in the development of pembrolizumab leading to this first approval for the treatment of malignant melanoma.
You can find the article here.
The U.S. Food and Drug Administration is advising consumers to be aware of products sold online claiming to prevent or treat the Ebola virus. Since the outbreak of the Ebola virus in West Africa, the FDA has seen and received consumer complaints about a variety of products claiming to either prevent the Ebola virus or treat the infection. There are currently no FDA–approved vaccines or drugs to prevent or treat Ebola. Although there are experimental Ebola vaccines and treatments under development, these investigational products are in the early stages of product development, have not yet been fully tested for safety or effectiveness, and the supply is very limited. There are no approved vaccines, drugs, or investigational products specifically for Ebola available for purchase on the Internet. By law, dietary supplements cannot claim to prevent or cure disease.
Taken from FDA Press Announcements
Northwestern Medicine scientists have demonstrated how metformin, a drug widely used to treat patients with type II diabetes, inhibits cancer progression. Recent studies suggest that the anti–diabetic drug prevents cancer progression, but how metformin diminishes tumor growth is not fully understood. Metformin works by decreasing insulin in the blood. It is postulated that since cancer cells need insulin to multiply, the drug slows down tumor growth by cutting the energy supply produced by their mitochondria. Navdeep S. Chandel, PhD, professor in Medicine–Pulmonary and Cell and Molecular Biology, and collaborators showed that metformin inhibits the function of mitochondrial complex I in human cancer cells, which reduces tumor burden. Mitochondrial complex I is a compound central to energy production in the cell. First authors are William W. Wheaton, graduate student in Walter S. and Lucienne Driskill Graduate Training Program in Life Sciences, and Samuel E. Weinberg, MD/PhD student in the Medical Scientist Training Program. The paper was published May 13 in eLife.
Taken from Northwestern University Feinberg School of Medicine News
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